De Niro said he's "deeply distressed" by the tragic loss.
Robert De Niro's grandson Leandro Anthony De Niro-Rodriguez has died.
"I'm deeply distressed by the passing of my beloved grandson Leo," De Niro told "Good Morning America" in a statement on Monday.
The "Raging Bull" actor continued, "We're greatly appreciative of the condolences from everyone. We ask that we please be given privacy to grieve our loss of Leo."
Leandro's mother Drena De Niro reacted to the death of her only child in a statement to "GMA," saying, "It is with immeasurable shock and and sadness that we say goodbye to our beloved son Leo."
"We thank you for the outpouring of love and support and ask that we are given privacy at this time to process this inconsolable grief," she added.
No details were provided about the manner of Leandro's death or the date he passed.
Drena De Niro was adopted by Robert De Niro when he was married to Diahnne Abbott, the actor's first wife. Drena De Niro is Abbott's daughter from a previous relationship.
